Knowledgeable.
Passionate. Visionary.

We Are Dedicated to Improving Your Internal Health

​We Are Dedicated to Improving Your Internal Health​

Ixcela: The Internal Fitness Company

For a variety of lifestyle-related reasons, the body’s internal biochemistry can be moved from a healthy, balanced state to a state that can lead to chronic disease. These chronic conditions include Alzheimer’s, Parkinson’s, ALS, and diabetes. Additionally, poor internal fitness may cause less severe but more common health issues, such as irritable bowel syndrome, acid reflux, and leaky gut.

The Ixcela approach restores internal health using a sophisticated test and individualized therapy. The Ixcela test identifies imbalances in key small molecules associated with the gut microbiome,and our individualized therapy restores these molecules to their proper levels with a personalized program that includes proprietary supplements, as well as personalized nutrition and fitness plans.

Ixcela has developed a pinprick blood test that looks at the levels of unique small-molecule metabolites shown through experimentation, peer-reviewed literature, and clinical studies to be associated with gut microbiome health. Analysis of the blood spot is performed by proprietary technology, including the Electrochemical Array (CoulArray™) invented by our co-founder Wayne Matson. Ixcela has unique supplements to help regulate specific biomarkers that are not at optimal levels. Thus, Ixcela provides a comprehensive approach to a) determining gut microbiome dysbiosis and b) providing actionable solutions to restoring proper gut microbiome health.

Optimal internal health Ixcela tests for metabolites

Ixcela technology is used and trusted by medical professionals including:


Emeran A. Mayer, MD
Gastroenterologist and Neuroscientist

Helena A. Santos-Martins, MD
Internal Medicine

Travis Wilkes, MD
Medical Director

Ixcela Team

Erika Ebbel Angle, Ph.D.

Erika Ebbel Angle, Ph.D.

CEO and Co-founder

Meet Biochemist Dr. Erika Ebbel Angle, the force behind Ixcela. Erika serves as Chief Executive Officer and is the cofounder of Ixcela.

Read Bio
Wayne Matson, Ph.D

Wayne Matson, Ph.D

Chief Scientist and Co-founder

Dr. Wayne Matson is co-founder of Ixcela and serves as its Chief Scientist. He has been at the center of the field of metabolomics for 30 years.

Read Bio
Amanda Brown, RDN, LDN

Amanda Brown, RDN, LDN

Registered Dietitian and Ixcela Program Expert

Amanda helps to ensure that Ixcela clients are successful in their health journey by guiding them through nutrition and lifestyle strategies based on their Ixcela test results to target their individualized goals.

Read Bio
Samantha Carley, MS, RDN, LDN

Samantha Carley, MS, RDN, LDN

Registered Dietitian and Ixcela Program Expert

Samantha supports Ixcela clients to improve their gut health, overall wellness, and reach their specific goals utilizing realistic and targeted recommendations based on the Ixcela test.

Read Bio
Shannon Hartsfield

Shannon Hartsfield

Director of Operations

Director of Operations Shannon Hartsfield oversees the day-to-day operations of Ixcela. With the support of others, she is responsible for HR, finance, IT, and working with the legal team.

Read Bio
Jonathon Kurtz

Jonathon Kurtz

Sales and Marketing Specialist

Sales and Marketing Specialist Jonathon Kurtz supports Ixcela’s pro partners by providing detailed product descriptions, explaining client benefits, and helping providers integrate the Ixcela testing into their practice.

Read Bio
Stephanie Marcey

Stephanie Marcey

Laboratory Technician

Laboratory Technician Stephanie Marcey performs essential duties to support the daily operations of Ixcela’s lab. She runs specimens, makes buffers, extractors and hydrators, and maintains the lab.

Read Bio
Samantha Matson

Samantha Matson

Director of Research and Development

Samantha Matson studied biology and chemistry at LIU. She began her love of science as a 4 year old when her father would bring her to his lab on weekends.

Read Bio
Samantha Nienow

Samantha Nienow

Chief Marketing Officer

Visual strategist and storyteller Samantha Nienow is responsible for designing the client's journey from taking the Ixcela test to feeling supported by implementing lifestyle changes after receiving results.

Read Bio
Juxhin Shehu

Juxhin Shehu

Clinical Laboratory Manager

Juxhin is a chemist who joined Ixcela in 2018. He received his bachelors from Salem State University in 2008, and since then his background experience has been in analytical chemistry and regulatory compliance.

Read Bio
Rachel Stuck, RD, LDN

Rachel Stuck, RD, LDN

Director of Wellness and Curriculum

Director of Curriculum and Wellness Rachel Stuck loves to dive into the latest gut microbiome and metabolite research.

Read Bio
Dr. Reggie Thomasson

Dr. Reggie Thomasson

Laboratory Director

Laboratory Director Dr. Reggie Thomasson oversees compliance and quality testing in the Ixcela lab.

Read Bio
Rachel Tortora

Rachel Tortora

Customer Service and Operations Specialist

Customer Service and Operations Specialist Rachel Tortora takes care of several behind-the-scenes operations at Ixcela.

Read Bio
YJ Tso

YJ Tso

Chief Technology Officer

Chief Technology Officer YJ Tso is committed to building a strong foundation of software and technology in order to responsibly and securely manage customers’ data, improve customer experience, optimize operations, and empower Ixcela’s scientific research and development.

Read Bio

Ixcela Advisory Team

Lillian So Chan

Lillian So Chan

Ixcela Science Communication Advisor

Read Bio
Dr. Manny W Radomski, PhD

Dr. Manny W Radomski, PhD

Ixcela Science Communication Advisor

Read Bio

Ixcela Board of Advisors

Dr. Emeran Mayer, MD

Dr. Emeran Mayer, MD

Gastroenterologist

Read Bio
Dr. Marvin Singh, MD

Dr. Marvin Singh, MD

Integrative Gastroenterologist

Read Bio
Dr. Travis Wilkes, MD

Dr. Travis Wilkes, MD

Family Medicine

Read Bio

Ixcela Board of Directors

Colin Angle

Colin Angle

Chairman of the Board, CEO and Co-founder of iRobot

Read Bio
Nick Soloway, Esq.

Nick Soloway, Esq.

Founder, Hayes Soloway, P.C.

Read Bio
Erika Ebbel Angle, PhD.

Erika Ebbel Angle, PhD.

CEO and Co-founder

Read Bio
Wayne R. Matson, Ph.D.

Wayne R. Matson, Ph.D.

Chief Scientist and Co-founder

Read Bio

The Ixcela Story—Collaboration + Innovation

Collaboration and in-depth analysis between seven scientists revealed ideas beyond diagnosis and therapy.

Ixcela was co-founded by Drs. Erika Ebbel Angle and Wayne Matson, who were aided by a group of outstanding scientists. Each team member had developed technologies and methods for the study of a range of diseases for diagnosis, predictive diagnostic risk factors, and specification of therapy (personalized medicine).

After deep analysis of the complex biochemical profiles for more than 1,000 compounds in tens of thousands of subjects, it became clear to us that the microbiome (the 6–10,000 species in the gut—the largest organ in the body) was a critical part of the biochemical web distinguishing normal from disease subjects. Understanding these webs could also allow the prediction of therapeutic response. Additionally, the biochemistry of the microbiome had direct links to the function of other organs, including the brain.

This led us beyond the ideas of diagnosis and therapy to the concept of promoting biochemical wellness (“internal health”) through measurement and control of the microbiome with specific, personalized intervention based on testing.

Intestinal cross-section Monitor chart


The inspiration for our company name “Ixcela” came from Ixchel—the ancient Mayan goddess of healing and medicine.

Find out how Ixcela can help you achieve your goals.

Get started